Black Urine

Black Urine The first symptom most AKU patients will experience is black or dark urine. Large quantities of a chemical called homogentisic acid (HGA) are excreted in the urine. If left to stand and exposed to the air, the HGA in urine will oxidise and start to turn...

DevelopAKUre

DevelopAKUre The DevelopAKUre programme was a series of major international clinical trials, run by a consortium of 12 European partners. It aimed to study a drug, called nitisinone, and assess its effectiveness in treating AKU. The DevelopAKUre clinical trials...

National AKU Centre (NAC)

National AKU Centre (NAC) The Robert Gregory National Alkaptonuria Centre Many people diagnosed with alkaptonuria (AKU) have difficulty accessing efficient and effective care to treat their AKU. For some, there has been a lack of local expertise and knowledge when...

What is AKU?

What is AKU? Alkaptonuria, also known as AKU or Black Bone Disease, is an extremely rare genetic condition, which can cause significant damage to the bones, cartilage and tissues of those affected. AKU normally only affects one in every 250,000 people worldwide. AKU...
13th International Scientific Conference on AKU

13th International Scientific Conference on AKU

  On the 27-28th July we hosted our 13th International Scientific Conference on AKU in Bratislava, Slovakia, which had a focus on treating hypertyrosinaemia in AKU and HT-1. This latest conference was our largest to date, with over 100 attendees from 19 countries...