Osteoarthritis Overtime, the build-up of homogentisic acid (HGA) leads to severe early onset osteoarthritis. HGA attacks the bones and cartilage, turning them black and brittle over time. Joints become less able to cope with activities which put them under strain,...
Black Urine The first symptom most AKU patients will experience is black or dark urine. Large quantities of a chemical called homogentisic acid (HGA) are excreted in the urine. If left to stand and exposed to the air, the HGA in urine will oxidise and start to turn...
Downloadable Resources This page provides resources for AKU patients, carers and their families. The information on this page includes leaflets about AKU and our services, impact reports, and newsletters. They are also available to download in 15 different Lanaguages....
DevelopAKUre The DevelopAKUre programme was a series of major international clinical trials, run by a consortium of 12 European partners. It aimed to study a drug, called nitisinone, and assess its effectiveness in treating AKU. The DevelopAKUre clinical trials...
AKU Society Blog Date: Month Jan Feb Mar Apr May Jun Jul Aug Sept Oct Nov Dec 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Liesbeth’s research visit to the University of Liverpool Read More 15th Feb 2024 Nitisinone programme for international patients...
